癫癎持续状态21例

Status Epileptic in 21 Children

目的探讨癫癎持续状态(SE)的常见病因、诱因及疗效,以期提高对本病的防范及治疗。方法对未经治疗者选用地西泮静脉推注或1%水合氯醛保留灌肠,症状控制者继以苯巴比妥钠针预防复发;症状未控制或入院前已在外院治疗而未好转者予注射用丙戊酸钠针静脉治疗,症状控制后继以丙戊酸钠糖浆预防复发。结果21例中,3例为癫癎未治疗,6例癫癎未经正规治疗,3例癫癎患儿发生于急性呼吸道感染,4例无诱因首发,3例发生于病毒性脑炎,停药后复发、脑外伤各1例。4例死亡,均为未经正规治疗患儿。丙戊酸钠对SE治疗有效,但对长时间发作者疗效不理想。结论SE的发生及预后与原发病密切相关,应强调预防为主。一旦发生SE,强调早识别、早治疗,以免发作时间过长而不可逆转。

Objective To investigate the comraon cause,inducement and treatment response in patients with status epileptic（SE） in children, in order to improve the level of prevention and treatment of the disease. Methods Valium and chloral hydrate be used in the patient untreated, followed with luminal. Deparkin injection be used in the patient uncontrolled, followed with syrup. Results Of 21 patients, 3 cases with epilepsy hadn＇t-been treated; 6 cases with epilepsy hadn＇t been treated regularlly; 3 cases with epilepsy place respiratory infection;4 cases were the first attack with no inducement; 3 cases were suffering from viral encephalitis. Four cases with epilepsy were died who hadn＇t been treated regularly. Deparkin might be helpful in treatment with SE, but poor control in patients with long time attacks. Conclusions The attack and prognosis of SE are closely relative to original sick. It is important to prevent the attack. Early diagnosis is the key factor to improve prognosis.