肛门置入米索前列醇对剖宫产术后出血的影响

EFFECT OF MISOPROSTOL INSERTED IN ANUS ON REDUCTION OF HEMORRHAGE AFTER CESAREAN SECTION

目的探讨剖宫产术后应用米索前列醇预防和减少子宫出血的效果。方法选择202例择期剖宫产产妇,根据关腹后止血及宫缩剂的使用情况,分为米索前列醇组及催产素组,分别为106、96例。观察组于打开宫壁、吸净羊水的同时,由台下人员将米索前列醇2片(200μg)经肛门放入产妇直肠;对照组采用传统方法,于胎儿娩出后立即宫壁注射催产素20u。比较胎儿取出后两组产妇的2h内经阴道出血总量、24h时阴道出血量。结果米索前列醇组出血量显著少于催产素组。结论米索前列醇用于预防和减少剖宫产术后出血具有方便、有效、安全、价廉的特点。

Objective To assess the effect of misoprostol in reduction and prevention of hemorrhage after cesarean seetion（CS）. Methods According to the use of hemostatie agents and oxytoein after CS, 202 patients were divided into two groups （ 106 . 96 in each group ） ： misoprostol group and oxytocin group. The total amount of vaginal bleeding during the period from the fetus out to the 2 hours and 24 hours were observed. Results The bleeding amount two hours after delivery in the misoprostol group was much less than that in the oxytoein group with a statistical significance. Conclusion Misoprostol is convenient, safe, effective and less expensive in reduction and prevention of hemorrhage.