基于杯[4]芳烃的选择性识别二酸的化学传感器

A novel calix[4]arene-based chemosensor for dicarboxylic acid

设计、合成了以杯[4]芳烃为平台，以氨基吡啶基团为双识别位点的新型化学传感器，并用红外光谱、质谱、核磁董拳和元素分析方法对其进行了表征。紫外和荧光光谱研究结果表明，该受体分子在二氯甲烷溶液中能选择性识别脂肪二酸,络合常数可达10^3～10^4L／mol，络合能力大小顺序为：丙二酸〉草酸〉丁二酸〉戊二酸〉已二酸。

A new chemosensor was prepared from a calix[4]arene platform and two 2-aminopyridine recognition sites, and its chemical structure was identified by FT-IR, MS-FAB, ^H-NMR,^13C-NMR and elemental analyses. UV-Vis and fluorescent titration experiments demonstrated that the molecular receptor was able to bind dicarboxylic acids in CH2Cl2 with apparent binding constants ranging from 10^3 to 10^4 L/mol,and its binding ability for dicarboxylic acids in the following order： malonic 〉 oxalic 〉 succinic 〉 glutaric 〉 adlpic.