摘要
目的研究神经外科开颅手术后颅内感染的危险因素,为预防提供依据。方法对神经外科开颅手术后的432例患者进行前瞻性调查。结果432例患者中,发生颅内感染67例,感染率为15.51%。留置引流管者颅内感染率为17.05%,较未引流者颅内感染率2.22%之差异有显著性(P〈0.05);手术时间≤4h者颅内感染率为6.90%,〉4h者颅内感染率为21.32%,两者差异有显著性(P〈0.01)。脑室引流的患者颅内感染率为24.30%,其他部位引流患者颅内感染率为3.68%,两者差异有高度显著性(P〈0.001)。引流管留置1~2d感染率为10.53%,3~4d为30.34%,≥5d为68.97%,三者间差异有高度显著性(P〈0.001)。结论开颅手术后颅内感染与手术持续时间和留置引流管,特别是脑室留置引流管有关。
Objective To study the risk factors for post-craniotomy intracranial infection in patients in department of neurosurgery, so as to provide reference for prevention. Methods Four hundred and thirty-two patients with craniotomy in department of neurosurgery were investigated prospectively. Results Sixty-seven of 432 patients developed intracranial infection, the infection rate was 15.51%. The intracranial infection rate in patients with drainage was 17.05 %, which was obviously higher than that (2.22%) in patients without drainage ( P 〈 0.05). The intracranial infection rate in patients whose duration of operation 44 h was 6.90%, which was obviously lower than that (21.32%) in patients whose duration of operation 〉4 h ( P 〈0. 001). The intracranial infection rate in patients with ventricular drainage was 24.30%, which was obviously higher than that (3.68%) in patients with other sites drainage ( P 〈 0.01). The intracranial infection rate in patients whose duration of drainage 1 - 2 d, 3 - 4 d and ≥5 d was 10.53%, 30.34% and 68.97% respectively ( P 〈 0. 001). Conclusion Post-craniotomy intracranial infection is related with duration of operation and drainage, especially ventricular drainage.
出处
《中国感染控制杂志》
CAS
2006年第3期214-215,218,共3页
Chinese Journal of Infection Control
关键词
神经外科
颅骨切开术
医院感染
颅内感染
导管
留置
department of neurosurgery
craniotomy
nosocomial infection
intracranial infection
catheters, indwelling