期刊文献+

逆转录病毒介导的慢性粒细胞白血病模型研究进展与应用 被引量:1

原文传递
导出
摘要 慢性粒细胞白血病(CML),是一种起源于骨髓内异常多能干细胞的骨髓增殖性疾病,以持续表达Bcr-Abl融合基因为特征。以逆转录病毒为载体,可使Bcr-Abl融合基因整合到细胞中持续表达,而形成CML模型。本文就逆转录病毒介导的CML模型研究进展与应用加以综述。
作者 杨东光 张日
出处 《国际输血及血液学杂志》 CAS 2006年第4期328-330,共3页 International Journal of Blood Transfusion and Hematology
  • 相关文献

参考文献17

  • 1Holyoake DT. Recent advances in the molecular and cellular biology of chronic myeloid leukemia : lesson to be learned from the laboratory. Br J Haematol, 2001, 113(1):11-23.
  • 2Mes-Masson AM, McLaughlin J, Daley GQ, et al. Overlapping cDNA clones define the complete coding region for the P210e-ab1 gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chrosome. Proc Natl Acad Sci U S A,1986, 83 (24):9768- 9772.
  • 3Daley GQ, Mclaughlin J, Witte ON, et al. The CML-specific P210 bcr/abl protein, unlike v-abl, dose not transform NIH/3T3 fibroblasts. Science, 1987, 237:532-535.
  • 4Daley GQ, Van Etten RA, Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210 bcr/abl gene of the Philadelphia chromosome. Science, 1990, 247:824-830.
  • 5Daley GQ, Van Etten RA, Baltimore D. Blast crisis in a murine model of chronic myelogenous leukemia. Proc Natl Acad Sci U SA, 1991, 88(24):11335-11338.
  • 6Gishizky ML, Johnson-White J, Witte ON. Efficient transplantation of BCR-ABL-induced chronic myelogenous leukemia-like syndrome in mice. Proc Natl Acad Sci U S A,1993, 90(8):3755-3759.
  • 7Zhang X, Ren R. Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony stimulating factor in mice: a novel model for chronic myelogenous leukemia. Blood, 1998, 92 (10): 3829-3840.
  • 8Pear WS, Miller JP, Xu L, et al. Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow. Blood,1998, 92(10): 3780-3792.
  • 9Wolff NC, Ilaria RL. Establishment of a murine model for therapy-treated chronic myelogenous leukemia using the tyrosine kinaseinhibitor STI571. Blood, 2001, 98(9): 2808-2816.
  • 10Wolff NC, Richardson JA, Egorin M, et al. The CNS is a sanctuary for leukemic cells in mice receiving imatinib mesylate for Bcr/Abl-induced leukemia. Blood, 2003, 101 (12) : 5010-5013

同被引文献16

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部