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急性髓系白血病中乳腺癌多药耐药蛋白基因的研究进展

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摘要 乳腺癌耐药蛋白(BCRP)是新近发现的一种肿瘤耐药相关蛋白,与P-gp和多药耐药相关蛋白(MRP)同属ABC转运蛋白超家族。本文对BCRP的发现、组织表达、结构特点、急性髓系白血病中多药耐药BCRP基因的表达及应用等方面的研究进展进行综述。
出处 《国际输血及血液学杂志》 CAS 2006年第4期338-340,共3页 International Journal of Blood Transfusion and Hematology
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  • 1Ross DD, Yang WD, Abruzzo LV, et al. A typical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitroxantron- selected cell lines. J Natl Cancer Inst,1999,91(6) :429-433.
  • 2Chen YN, Mickley LA, Schwartz AM, et al. Characterization of adriamycin resistance human breast cancer cells which display over expression of a novel resistance-related membrance protein. J Biol, 1990,26(5) :10073-10080.
  • 3Doyle LA,Yng W, Abruzzo LV, et al. A multidrug transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA,1998,95(26): 15665- 15670.
  • 4Mao Q, Unadkat JD. Role of the breast cancer resistance protein(ABCG2)in drug transport. AAPS J, 2005,7( 1 ) : 118-133.
  • 5Brian L, Anne M, Barnes YX, et al. Low levels of ABCG2 expression in adult AML blast samples. Blood, 2002, 12(15):4594-4601.
  • 6Uggla B, Stahl E, Wagsater D, et al. BCRP mRNA expression clinical outcome in 40 adult AML patients. Leukemia Res,2005,29(2) : 141-146.
  • 7Imai Y, Nakane M, Kage K, et al. MolC421 Apolymophism in the human breast cancer resistance gene associated with low expression of Q141K protein and low level drug resistance. Cancer Ther,2002,1(18) :611-616.
  • 8Xu JK, Liu Y, Yang YY, et al. Characterization of oligomeric human half-ABC transporter ATP-binding cassette G2. J Biol Chem, 2004,279(19) :19781-19789.
  • 9Albermann N, Schmitz FH, Zgraggen K, et al. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver. Biochem Pharmacol, 2005,70(6):949-958.
  • 10Dorina M, Vellenga E, Scheffer GL, et al. Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia. Blood, 2002,99 (12) : 3763-3770.

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