1Doble BW,Woodgett JR.GSK-3:tricks of the trade for a multitasking kinase.J Cell Sci,2003,116:1175-1186.
2Jope RS,Johnson GVW.The glamour and gloom of glycogen synthase kinase-3.Trends Biochem Sci,2004,29:95-102.
3Ahn H J,Kim YS,Kim JU,et al.Mechanism of taxol-induced apoptosis in human SKOV3 ovarian carcinoma cells.J Cell Biochem,2004,91:1043-1052.
4Ougolkov AV,Fernandez-Zapieo ME,Savoy DN,et al.Glycogen synthase kinase-3 β participates in nuclear factor κB-mediated gene transcription and cell survival in pancreatic cancer cells.Cancer Res,2005,65:2076-2081.
5Shakoori A,Ougolkov A,Yu ZW,et al.Deregulated GSK3β activity in colorectal cancer:its association with tumor cell survival and proliferation.Biochem Biophys Res Commun,2005,334:1365-1373.
6Rask K,Nilsson A,Brannstrom M,et al.Wnt-signalling pathway in ovarian epithelial tumours:increased expression of β-catenin and GSK3β.Br J Cancer,2003,89:1298-1304.
3Charles JS. He pezcoller lecture: cancer cell cycles revisited, Cancer Res, 2000, 60: 3689-3695.
4Lioyd RV, Erickson LA, Long J, et al. A multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am J Pathol, 1999,154:313-323.
5Tatjana V, Achenbach, Rolf Muller, et al. Synergistic antitumor effect of chemotherapy and antisense-mediated ablation of the cell cycle inhibitor p27, Clin Cancer Res,2000,6: 3006-3014.
6Koike C, McKee TD, Pluen A, et al. Solid stress facilitates spheroid formation: potential involvement of hyaluronan. Br J Cancer, 2002, 75:947-953.
7Frankel A, Buckman R, Kerbel RS. Abrogation of taxol-induced G2-Marrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids. Cancer Res, 1997,57:2388-2393.
8Hamilton G. Multicellullar spheroids as an in vitro tumor model. Cancer Lett, 1998,131:29-34.
9St Croix B,Florenes VA, Rak JW ,et al. Impact of the cyclin-dependent kinase inhibitor p27 on resistance of tumor cells to anti-cancer agents. Nature Med, 1996, 2:1204-1210.
10Alan MG, Deborah LS, Marius ZR. Nucleic acid therapeutics: state of the art and future propects. Blood, 1998,92: 712-736.
3Doble B W,Woodgett J R, GSK-3: tricks of the trade for a multitasking kinase[J]. J Cell Sci,2003,116(Pt 7) :1175-1186.
4Erdal E, Ozturk N, Cagatay T, Eksioglu-Demiralp E, Ozturk M. Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells[J]. Int J Cancer, 2005,115 : 903-910.
5Macanas Pirard P,Yaacob N S,Lee P C, Holder J C, Hinton R H,Kass G E. Glycogen synthase kinase-3 mediates acetaminophen induced apoptosis in human hepatoma cells[J]. J Pharmacol Exp Ther,2005,313:780-789.
6Steeg P S. Tumor me*astasis: mechanistic insights and clinical challenge[J]. Nat Med, 2006,12:895-904.
7Rinker-Schaeffer C W,Chekmareva M A, Mohler J L. The role of motility proteins and metastasis suppressor genes in prostate cancer progression[J]. Stem Cells, 1996,14 : 508-516.
8Khanna C, Hunter K. Modeiing metastasis in vivo[J]. Carcinogenesis, 2005,26: 513-523.
9Nowicki M O, Dmitrieva N, Stein A M, Cutter J L, Godlewski J, Saeki Y, et al. Lithium inhibits invasion of giioma cells: possible involvement of glycogen synthase kinase-3[J]. Neuro Oncol,2008,10:690-699.
10Jiang H, Guo W, Liang X, Rao Y. Both the establishment and the maintenance ot neuronal polarity require active mechanism: critical roles of GSK-3β and its upstream regulators[J]. Cell, 2005,120: 123-135.
