静脉营养支持在治疗COPD并Ⅱ型呼吸衰竭中的临床观察

Clinical observation on intravenous nutritional support in the treatnent of COPD with typeⅡ respiratory failure

目的:观察静脉营养支持在治疗慢性阻塞性肺疾病(COPD)并Ⅱ型呼吸衰竭中的临床疗效。方法:将116例COPD并Ⅱ型呼吸衰竭患者随机分成两组:治疗组56例,对照组60例。两组均予抗感染、吸氧、解痉平喘、化痰、纠正酸碱失衡及电解质紊乱等治疗,疗程4周。治疗组在正常要素饮食基础上,予白蛋白、脂肪乳、复方氨基酸等行静脉营养支持治疗;对照组仅给予正常要素饮食,不行以上静脉营养治疗。结果:治疗组与对照组比较,人体测量值增加、肺功能改善、血清白蛋白升高,两组比较差异有显著性(P<0.05)。结论:静脉营养支持治疗可明显改善COPD并Ⅱ型呼吸衰竭患者的症状和体征;提高血清白蛋白;明显改善人体测量值、血气分析及肺功能。

Objective：To observe the clinical effect of intrarenous nutritional support in the treatnent of chronic obstruction pulmonary disease（COPD）with type Ⅱ respiratory failure.Methods：116 cases of COPD with type Ⅱ respiratory failure were randomly divided into two groups,the treatment group（56 cases）and control group（60 cases）.Anti-infection,oxyen inhalation,spasmolysis and anti-asthma,ehminating phlegm,correcting acid-base inbalance and electrolyte disorder and so on were used in both groups for 4 weeks.besides this the treatment group was added with albumin,fat milk and compound amino-acid at the same time.Results：The treatment group was compared with the contro group with a significant difference in increasing anthropometric value,improving lung function and rising serum albumin （P〈 0.05）.Conclusion：Intravenous nutritional supporting treatment can significantly improve the symptoms and funcional indicators,raise serum albumin and improve anth ropometric value,blood gaseous analysis and lung function in patients of COPD with type Ⅱ respiratory failure.