期刊文献+

利用干细胞生产转基因动物研究进展 被引量:2

Progress on producing transgenic animals with stem cells
下载PDF
导出
摘要 干细胞是个体发育过程中遗留在机体的各个部位、保持着原始状态的一些细胞。在临床上,干细胞有着重要的应用价值。文章概述了利用干细胞生产转基因动物的现状、发展、原理和优点等,以为转基因动物的生产提供借鉴。 Stem cells ,harboured in some parts of organisms ,remain primitive during the development. They play a key role in clinical application. In this paper,the status quo,development,mechanism,and advantage to provide references for producing transgenic animals were summarized.
出处 《西北农林科技大学学报(自然科学版)》 CSCD 北大核心 2006年第7期37-40,共4页 Journal of Northwest A&F University(Natural Science Edition)
基金 国家自然科学基金项目(39970363) 国家"973"项目(G199954301)
关键词 干细胞 转基因动物 基因转移技术 stem cell transgenic animal transgenic technology
  • 相关文献

参考文献29

  • 1Gossler A,Doetschmsn T,Korn R,et al.Transgensis by means of blastocyst-derived embryonic stem cell lines[J].Proc Natal Acad USA,1986,83:9065-9069.
  • 2Wood S A,Pascoe W S,Schmidt C,et al.Simple and efficient production of embryonic stem cell embryo chimeras by coculture[J].Proc Nalt Acad Sci USA,1993,365:6441-6443.
  • 3郝捷,冯波,王建辰.转基因动物研究进展[J].动物医学进展,2004,25(1):1-4. 被引量:7
  • 4Bradley A,Evans M,Kaufman M H,et al.Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines[J].Nature,1984,309(5965):255-256.
  • 5Magin T,Mc Whir J,Melton D W.A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency[J].Nucleic Acids Res,1992,20:3795-3796.
  • 6程萱,周江,谭晓红,程竞,杨晓.遗传修饰小鼠胚胎干细胞种系嵌合体小鼠的研制[J].生物技术通讯,2003,14(1):1-3. 被引量:4
  • 7Maeda T,Yamakawa Y,Masuda K,et al.Distribution of blastodermal cells transferred to click embryos for chimera production using windowed eggs[J].Br Poult Sci,1997,38(3):241-244.
  • 8Hong Y H,Moon Y K,Jeong D K,et al.Improved transfection efficiency of chicken gonadal primordial germ cells for the production of transgenic poultry[J].Transgenic Res,1998,7 (4):247-252.
  • 9Reynaud M G.The localization of primordial germ cells in Japanese quail embryos using a technic of ultraviolet irradiation[J].C R Acad Sci Hebd Seances Acad Sci D,1976,282(12):1195-1198.
  • 10Aige-Gil V,Simkiss K.Sterilisation of avian embryos with busulphan[J].Res Vet Sci,1991,50(2):139-144.

二级参考文献37

  • 1杨静平,孔玉英.SA脂质体—高效介导DNA转染的新试剂[J].生物化学与生物物理学报,1993,25(3):231-238. 被引量:15
  • 2胡新立,尚克刚.6个小鼠ES细胞系的建立和鉴定[J].北京大学学报(自然科学版),1996,32(2):248-253. 被引量:41
  • 3冼美薇,吴白燕,胡新立,尚克刚,吴鹤龄.通过显微注射法构建ES细胞(MESPU 13)嵌合小鼠[J].遗传,1996,18(1):7-10. 被引量:5
  • 4柴桂萱,韩嵘,尚克刚.C57 BL/6J小鼠ES细胞系的建立及其特性分析[J].细胞生物学杂志,1996,18(3):121-126. 被引量:15
  • 5Mclean D J, Johnston D S, Russell L D, et al. Germ cell transplantation and the study of testicular function. Trends Endocrinol Metab, 2001, 12(1): 16 - 21.
  • 6Meachem S, Schonfeldt V N, Schlatt S, et al. Spermatogonia: stem cells with a great perspective. Reproduction, 2001, 121:825 - 834.
  • 7Schalatt S. Germ cell transplantation. Mol Cell Endocr, 2001, 186:163 - 167.
  • 8Izadyar E Creemers L B, van Dissel-Emiliani F M F. Spermatogonial stem cell transplantation. Mol Cell Endocr, 2000, 169:21 - 26.
  • 9Nagano M, Shinohara T, Avarbock M, et al. Retrovirus-mediated gene delivery into male germ line stem cells. FEBS Letters, 2000,475:7 - 10.
  • 10Nagano M, Brinster C J, Orwig K E, et al. Transgenic mice produced by retroviral transduction of male germ-line stem cells.Proc Natl Acad Sci USA, 2001, 98(23): 13090 - 13095.

共引文献50

同被引文献31

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部