黄三七皂苷类化学成分(Ⅱ)

Studies on identification of saponins from Souliea vaginata Ⅱ

目的：开发利用黄三七Souliea vaginata资源，从中寻找新的天然活性成分。方法：利用各种色谱技术进行分离纯化，根据理化性质和各种波谱技术进行结构鉴定。结果：分离鉴定了6个三萜皂苷，分别为25（R）-甲氧基阿特素（1）、12β-羟基升麻醇木糖苷（2）、7，8-二去氢-25-甲氧基-24-O-乙酰升麻醇木糖苷（3）、25-甲氧基-24-O-乙酰升麻醇木糖苷（4），24-O-乙酰升麻醇木糖苷（5）和7，8-二去氢-24-O-乙酰升麻醇木糖苷（6）。结论：化合物1为新的天然产物，化合物2—6均为本属首次分离。

AIM： To find active constituents from the root of Sotdiea vaginata. METHOD： Various column chromatographic techniques were applied for isolation and purification. The structures were elucidated by spectral evidence. RESULT： Six compounds were isolated and identified as 26 （ R ）-methoxyactein （1）, 12β- hydroxycimigenol-3- O-β-D-xylopyranoside （2）, 24- O-acetyl-25- O-methyl-7, 8-didehydroshenmanol-3-O-β-D-xyloside （ 3 ）, 25-O-methyl-24-O-acetyl hydroshengmanol-3-O-β-D-xyloside （ 4 ）, 24 - O- acetylhydroshengmanol-3- O-β- D-xyloside （ 5 ）, and 7, 8-didehydro-24- O-acetylhydroshengmanol-3-O-β- D-xyloside （ 6 ）. CONCLUSION： Compound 1 is a new natural product; compounds 2 ～ 6 were obtained from this genus for the first time.