某养鸡场禽霍乱分离菌对常用抗菌药物的敏感性研究

Medicinal Sensitivity Test of Pasteurella Multocida Strain Isolated from Dead Chicken in a Hennery

从六安地区某养鸡场禽霍乱病鸡上分离到1株禽多杀性巴氏杆菌,采用纸片扩散法和试管稀释法分别测定了青霉素钾、土霉素、硫酸卡那霉素、硫酸庆大霉素、硫酸链霉素、复方新诺明、甲砜霉素、氟哌酸、环丙沙星和恩诺沙星等10种药物对分离菌的体外抗菌活性。结果表明分离到的禽多杀性巴氏杆菌对青霉素钾和土霉素耐药;对硫酸卡那霉素、硫酸庆大霉素、硫酸链霉素、甲砜霉素、氟哌酸敏感;对复方新诺明、环丙沙星和恩诺沙星极敏感。两种测定方法得到的结果一致。因此复方新诺敏、环丙沙星和恩诺沙星可作为目前该发病场防治禽霍乱的首选药物。

One Pasteurella multocicla strain was isolated from dead chickens in a hennery and its medicinal sensitivity to ten antibiotic medicines was studied by filter paper diffusion method and tube dilution method. The results showed that the isolated Pasteurella multocida strain was resistant to benzylpenicillin potassium and oxytetracycline and sensitive to kanamycin, streptomycin, gentamyein, Thiamphenicol, norfloxacin and highly sensitive to sinomin compositea, ciprofloxacin and enrofloxacin. The two different methods of medicinal sensitivity test got consistent results. Therefore, sinomin compesitea, ciprofloxacin and enrofloxacin were preferred medicine in treating fowl cholera in this hermery presently.