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GPⅡb/Ⅲa受体拮抗剂在急性冠状动脉综合征的临床应用进展

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作者 方哲 金海
机构地区 延边大学附属医院
出处 《吉林医学》 CAS 2006年第7期848-850,共3页 Jilin Medical Journal
关键词 急性冠脉综合征 糖蛋白GPⅡb/Ⅲa受体拮抗剂
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献19

  • 1Ferguson JJ,Lau TK.New antiplatelet agents for acute coronary syndromes[J].Am Heart J,1998,135:S194.
  • 2Peerlinck K,De-Lepeleire I,Goldberg M,et al.A selective nonpeptide platelet glycoprotein Ⅱ b/Ⅲa antagonist,it active in man[J].Circulation,1993 ,88(4):1512.
  • 3黄震华,徐济民.心肌缺血治疗中抗血小板药物应用进展[J].新药与临床,1997,16(4):231-233. 被引量：14
  • 4Coller BS,Peerschke EI,Scudder LE,et al.A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombosthenic like state in normal platelets and binds to glycoproteins Ⅱb and/or Ⅲa[J].J Clin Invest,1983, 72:325.
  • 5The EPISTENT Investigators.Randomised placebo controlled and balloon angioplasty controlled trial to assess safety of coronary stenting with use of platelet glycoprotein-Ⅱ b/Ⅲ a blockade.Evaluation of Platelet Ⅱ b/Ⅲ a Inhibitor for Stentins[J].Lancet,1998, 352:87.
  • 6The EPIC Investigators.Use of monoclonal antibody directed against the platelet glycoproteinⅡb/Ⅲa receptor in highrisk coronary angioplasty[J].N Engl J Med,1994,330(14):956.
  • 7Simoons ML,GUSTO Ⅳ-ACS Investigators.Effect of Glycopro tein Ⅱ b/Ⅲ a receptor blocker abciximab on outcome in patients with acute coronary syndromes without early coronary revascu larisation:the GUSTO Ⅳ-ACS randomised trial[J].Lancet,2001 ,357(9272):1915.
  • 8Scarborough RM,Naughton MA,Teng W,et al.Design of potent and specific integrin antagonists.Peptide antagonists with high specificity for glycoprotein Ⅱ b/Ⅲ a[J].J Biol Chem,1993, 268:1066.
  • 9Jennings L,Tardiff B,Philips D,et al.Comparison of recept or occupancy and platelet aggregation response of epifibatide administered intravenously in patients with unstable angina or non Q wave myocardial infarction[J].J Am Coll Cardiol,1998 ,31 (2A):93A.
  • 10Mahaffey KW,Harrington RA,Simoons ML,et al.Stroke in patients with acute coronary syndromes:Incidence and outcomes in the platelet glycoprotein Ⅱ b/Ⅲ a in unstable angina.Receptor suppression using integrilin therapy (PURSUIT) trial.The PURSUIT Investigators[J].Circulation,1999, 99(18):2371.

二级参考文献1

  • 1Kun S K，Am J Physiol，1994年，267卷，H488页

共引文献13

吉林医学
2006年 第7期

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