慢性前列腺炎患者抑郁障碍的调查分析

Epidemiological Study of Chronic Prostatitis Patients with Depression Symptoms

目的:了解慢性前列腺炎(CP)患者抑郁障碍的患病情况,探讨抑郁障碍与CP的相互关系。方法:采用Zung抑郁自评量表(SDS)、国际前列腺炎症状指数表(CPSI)、国际勃起功能指数表(IIEF-5)及自制的相关情况调查表对1 500例门诊就诊的CP患者进行调查。结果:回收有效问卷1 426例,SDS总分为(44.24±10.20)分,显著高于国内常模(P=0.000)。按≥53分为划界分,共有抑郁症状者309例,占21.7%,其中轻度抑郁者176例,占12.3%;中度抑郁者114例,占8.0%;重度抑郁者19例,占1.3%。患者在SDS诸多表现中突出的症状正是CP的诱因和加重因素。同时,SDS积分与病程、CPSI积分、IIEF积分、就诊次数、治疗费用显著相关(P<0.01),而与患者年龄、前列腺液白细胞计数无关。结论:CP患者大多存在抑郁障碍;抑郁障碍与CP密切相关,是导致CP反复发作、迁延不愈、疗效不佳的重要因素之一。

Objective： To study the depression symptoms in chronic prostatitis （CP） patients, and explore the correlation between depression symptoms and CP, Methods： The Zung self-rating depression scale （SDS）, NIH-CPSI, IIEF-5, and a self-designed questionnaire were employed in 1 500 cases of CP patients. Results： A total of 1 426 effective questionnaires were collected. The mean score of SDS was （44.24 ± 10.20）, significantly higher than that of the domestic norm（P = 0. 000）. With the score limitation set at 353, 309 （21.7%） of the CP patients had symptoms of depression, of whom 176（ 12.3% ） were rated by SDS as in the mild, 114 （8.0%） in the moderate and 19（ 1.3% ） in the severe state of depression. The dominating symptoms as listed in SDS were exactly the stimulating and provoking factors of CP. The scores of SDS were significantly correlated with disease course, CPSI score, IIEF score and times and cost of treatment （P 〈 0.01 ）, while no correlation was observed with age and WBC counts in EPS. Conclusion ： CP patients mostly have depression problems, which are closely correlated with CP and contribute to the recurrence, refractoriness and discontented outcome of the disease.