低糖类肠内营养制剂对高血糖危重症病人的影响

The effect of enteral nutrition support with low carbohydrate formula in critically ill patients with hyperglycemia

目的:评价低糖类肠内营养制剂对高血糖危重症病人的影响。方法:将52例病人随机分成研究组和对照组,分别给予相同热量和氮量的肠内营养支持。研究组用康全达,对照组用能全力。观察治疗前后血糖、血浆清蛋白、血红蛋白、血脂、二氧化碳分压和氧分压的变化。结果:研究组病人空腹血糖水平变化小,无需加用胰岛素;对照组病人空腹血糖明显升高,需加用胰岛素治疗。研究组治疗后与对照组比较,血气分析指标变化差异有显著性意义(P<0.05)。两组病人肠内营养支持后的清蛋白和血红蛋白水平明显升高,而血脂变化差异无显著性意义。结论:低糖类肠内营养制剂对控制危重症病人的高血糖、改善呼吸功能和营养状况有一定的作用。

Objectives ： To study the effect of low carbohydrate formula＇s enteral nutrition in critically ill patients with hyperglycemia. Methods ：52 patients were randomly divided into control group and study group. The control group was given Nutrison and the study group was given Diasip. Blood glucose, blood lipid, serum protein, PaCO2 and PaO2 were measured before and after therapy. Results：The fasting blood glucose was significantly increased in patients having received Nutrison and did need insulin treatment. The fluctuation of blood glucose was less in patients who had used Diasip and didn＇t need insulin. The changes of serum protein were significant after therapy and were not significant between groups. The changes of serum lipid were significant after therapy and were not significant between groups. Conclusion：Diasip can control blood glucose and improve nutritional status and respiratory failure in critically ill patients with hyperglcemia.