摘要
目的:探讨银杏叶提取物(GBE)舒血宁注射液治疗后,颈动脉硬化性斑块的改变。方法:对伴颈动脉硬化斑块的急性脑梗死患者38例使用舒血宁注射液静脉滴注治疗(治疗组),15天后与维脑路通治疗46例(对照1组)及复方丹参治疗54例(对照2组)的患者比较。采用多普勒超声检查观察治疗前后颈动脉内膜-中层厚度的改变情况。结果:使用舒血宁注射液治疗后,经多普勒超声检查发现,患者颈动脉内膜-中层厚度(IMT)比治疗前改善,且明显优于对照1组和对照2组(P<0.05)。结论:应用多普勒超声检测IMT的方法提示银杏叶治疗粥样硬化斑块有临床应用前景。其抗氧化、清除自由基作用可能改善了颈动脉硬化斑块。
Objective: To investigate the variation of indurative plaque in carotid by treating of Ginkgo Biloba extract (GBE) combined with Suxuening injection. Methods:38 cases with acute cerebral infarction and indurative plaque in carotid were mainlined by Suxuening injection for 15 days, 46 cases by Venoruton tables and 54 cases by Fufangdanshen tables. The variation of intima media thickness (IMT) of carotid before and after treatment were observed and compared by color Doppler uhrasonography. Results:IMT in cases treated by Suxuening injection were obviously improved and the effect was better than that treated by Venoruton tables and Fufangdanshen tables. Conclusion:IMT observation by Doppler ultrasonography show GBE has a good clinical foreground in treating carotid atherosclerosis.
出处
《浙江中西医结合杂志》
2006年第8期465-466,共2页
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
基金
温州市科技计划项目(No:Y2003A086)
关键词
颈动脉斑块
彩色多普勒
银杏叶提取物
Ginkgo Biloba extract color Doppler ultrasonography carotid plaque