摘要
在实验室大规模主要虫生真菌药物模型筛选的基础上,对安徽农业大学虫生真菌实验室保存的菌株蛹拟青霉[Paecilomyces m ilitaris(Kob.)B rown&Sm ith ex L iang]RCEF0718的抗肿瘤活性进行了进一步的研究。通过硅胶柱及凝胶柱的多步分离纯化,得到的化合物对多种肿瘤细胞具备良好的抑制活性。
Based on the screening of entomogenous deuteromycetes for pharmaceutical use, antitumor activity, extraction, purification and structure identification of RCEF0718 from Cordyceps mititaris were conducted, and several compounds ( 〉 95 % ) was isolated and purified for further research.
出处
《安徽农业大学学报》
CAS
CSCD
北大核心
2006年第3期406-410,共5页
Journal of Anhui Agricultural University
关键词
蛹虫草
分离纯化
抗肿瘤
Paecilomyces militaris
purification
antitumor