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新生儿期使用糖皮质激素对神经系统的不良反应 被引量:7

Adverse Effect on Nervous System of Postnatal Corticosteroid Treatment
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摘要 近年研究显示,新生儿期,尤其是新生儿早期糖皮质激素治疗对中枢神经系统可能存在诸多不良反应,如对脑发育的长期影响可导致精神运动发育异常、脑瘫发生率增加和认知行为异常。其作用机制尚不明确,可能与糖皮质激素治疗促进神经细胞凋亡及影响神经细胞分化增殖等有关,故提出除非有严格的适应证,应尽量避免新生儿期应用糖皮质激素。
作者 袁琳 陈超
出处 《国际儿科学杂志》 2006年第4期222-224,共3页 International Journal of Pediatrics
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参考文献17

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