天然生物活性陶瓷珍珠层在骨组织修复中的应用

The application of nacre,a type of natural bioactive ceramic,in bone tissue reconstruction

珍珠层是一种天然的纳米生物陶瓷材料,一直是生物矿物材料学者研究的焦点。本文根据国外文献有关利用珍珠层作为骨植入材料的研究报道,就珍珠层的生物相容性和可降解性,及其所具有的骨诱导和骨传导作用的动物临床实验结果,进行了综合分析和论述。认为珍珠层是一种很有前途的骨植入材料,提出了今后研究的方向。

Recent advances in nacre used as bone implant are reviewed in this paper. The experiments show that nacre, a type of natural nano-bioceramic material, when used as bone implant for reconstruction of bone defects, is not only biocompatible and biodegradable, but also osteoconductive and osteoinductive. It is likely that nacre will become a good candidate for bone graft substitution in future.