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从猪去氧胆酸甲酯表观合成角鲨多胺 被引量：3

Formal Synthesis of Squalamine from Methylhyodeoxycholanate
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摘要 以猪去氧胆酸甲酯为原料,经15步反应以总产率5.6%表观合成具有抗菌、抗癌活性的海洋甾体角鲨多胺. A marine steroid squalamine with antibacteria and antitumor activity was formally synthesized in 15 steps with 5.6% overall yield from methylhyodeoxycholanate
作者 沈季铭 周向东 周维善
机构地区 中国科学院上海有机化学研究所
出处 《化学学报》 SCIE CAS CSCD 北大核心 2006年第14期1513-1516,共4页 Acta Chimica Sinica
基金 国家自然科学基金(No.20272068)资助项目.
关键词 角鲨多胺 猪去氧胆酸甲酯 表观合成 squalamine methylhyodeoxycholanate formal synthesis
分类号 TQ463.2 [化学工程—制药化工]
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参考文献14

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同被引文献19

  • 1王锺麒,阙浩泉,姜立中,周维善.猪去氧胆酸的化学Ⅰ.△~5-7-酮胆烷酸甲酯系列的还原研究[J].有机化学,1989,9(1):83-88. 被引量：4
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化学学报
2006年 第14期

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