神经垂体少见肿瘤15例临床病理分析

A clinicopathological analysis of 15 cases of the rare neurohypophysis tumors

以光镜、电镜、组化和免疫组化等方法，研究了１５例发生于神经垂体（包括漏斗突、漏斗柄和正中隆起）的少见肿瘤：星形细胞瘤１２例（其中３例伴垂体腺瘤、１例伴灶性节细胞增生）；节细胞瘤２例（１例伴侵袭性垂体腺瘤）；颗粒细胞瘤１例。临床均有闭经泌乳等内分泌症状和视力改变及内分泌检验异常等。因瘤体多较小，且质地稀软，临床、手术、放射和病理检查常被忽视。手术疗效佳，术后短期内症状体征消失或明显改善。此外，还探讨了节细胞瘤和颗粒细胞瘤的起源，讨论了临床、手术、放射和病理检查等应注意的问题等。

cases of the rare neurohypophysis tumors occurring in the region of hypothalamus-neurohypophysis(including infundibular process and its stalk and median eminece) were studied by light,electron microscopy, histochemical and immunohistochemical techniques. This study included 12 cases of astrocytoma, 2 case of gangliocytoma and 1 case granulocytoma. The apparent endocrinic symptoms and signs were attributed to the compression and destruction of the narrow pathway between the hypothalamic nuclei and pituitary. The tumors were very small and soft, hence often neglected clinically and also in surgical, radiological and pathological examinations. Operative effect was good. The origin of the ganglicoytoma and granulocytoma and points relevent to the clinical, operative, radiological and pathological diagnosis were discussed.