特发性全身性癫痫的临床与磁共振波谱研究进展

Advances on Idiopathic Generalized Epilepsy and Magnetic Resonance Spectrum Researches

特发性全身性癫痫(idiopathic generalized epilepsy,IGE)是一组症状复杂的临床症候群,易漏诊、误诊,且发病机制尚未完全阐明。以往的研究仅限于动物实验的方法检测其脑内的代谢变化,现在随着磁共振波谱(Magnetic Resonance Spectroscopy,MRS)的应用,无创地从生化代谢水平上研究活体已成为现实,为这一类疾病的研究打开了新的局面。文章综述了IGE的分类、亚型、临床特点及近几年来MRS在这一领域中的研究成果。

Idiopathic generalized epilepsy （IGE） is a complicated clinical syndrome. It is easy to be misdiagnosed, and its pathogenesy is still not elucidated literally. Early researches have been limited to animal experiment of detecting metabolism of brain. With the development of magnetic resonance spectrum（MRS）, studying in vivo tins come ture on file biochemistry metabolism＇ s level, which makes a new breakthrough for us to continue research of IGE afterward. Tiffs article reviews the types, clinical features and research achievemens of IGE for the past few years.