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核体蛋白Sp110及其生物学功能 被引量：4

Nuclear Body Sp110 and Its Biological Functions
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摘要 Sp110是最近发现的可能与结核易感性相关的新基因,是核体蛋白Sp100/Sp140家族中的一员,包含了Sp100区,SAND区,核定位序列(NLS)以及细胞核激素受体结合域(NRB)等多种功能结构区。在基因转录,激素受体信号传递,细胞凋亡,病毒复制等方面都有重要作用。 Sp110, a newly identified gene, which might be associated with tuberculosis, is a member of the Sp100/Sp140 family of nuclear body components. It contains motifs that are involved in Sp100 domain, SAND domain, nuclear localization signal and the NRB motif LXXLL. It plays an important role in gene transcription, nuclear hormone receptor signal transduction, apoptosis, and viral replication.
作者 周丹 李革
机构地区 重庆医科大学流行病学教研室
出处 《医学分子生物学杂志》 CAS CSCD 2006年第4期271-274,共4页 Journal of Medical Molecular Biology
关键词 Sp110核体蛋白 病毒感染 结核 Sp110 nuclear body viral infection tuberculosis
分类号 R373.1 [医药卫生—病原生物学]
  • 相关文献

参考文献20

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二级参考文献20

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同被引文献26

  • 1安雅臣,冯福民,袁聚祥,纪春梅,王育华,郭梅,邓小娟,高宝霞,王东,刘茜.NRAMP1基因INT4和3’UTR位点多态性与肺结核易感性的研究[J].中华流行病学杂志,2006,27(1):37-40. 被引量：19
  • 2冯福民,王东,郭梅,刘茜,高宝霞,安雅臣,纪春梅,孙永红.MBP-52位点多态性与肺结核易感性的病例对照研究[J].现代预防医学,2007,34(3):438-440. 被引量：6
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  • 4Singh A, Gaughan JP, Kashyap VK, et al. SLCI 1 A1 and VDR gene vari- ants and susceptibility to tuberculosis and disease progression in East In- dia[J]. Int J Tubere Lung Dis ,2011,15 ( 11 ) : 1468 - 1474.
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引证文献4

二级引证文献7

医学分子生物学杂志
2006年 第4期

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