期刊文献+

CA125用于卵巢癌随访的评价性研究:由患者的选择引起的临床实践的改变

A study to evaluate the use of CA125 in ovarian cancer follow-up:A change in practice led by patient preference
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摘要 Objectives. To evaluate the use of CA125 in the follow- up of women with epithelial ovarian cancer in the Cambridge Gynaecologic Oncology Centre. To institute changes depending on patients’ preferences. Methods. A patient questionnaire was developed on follow- up, CA125 estimation and patient education in epithelial ovarian cancer and CA125. Initially, 100 patients were evaluated, and a change in practice was instituted. This was reevaluated using the same patient population. Results. 22/22 patients in clinic, and 68/78 patients who received the questionnaire by post, completed and returned it (n = 90). 81% wanted CA125 results available at clinic follow- up visits, with 82% willing to have the blood test done at their GP surgery before attending outpatients. CA125 follow- up practice was changed accordingly. This change was re- evaluated. A second questionnaire was sent to 35 surviving patients from the first cohort. 31/35 (90% ) responses were received. Five patients were either no longer on follow- up, being ≥ 5 years from completing their original treatment or were being monitored elsewhere, leaving an 87% response rate (26/30). 92.3% felt that having CA125 results available in clinic had enhanced the quality of their follow- up. Patient education and basic understanding of CA125 also improved, with 88.5% aware of its role. Conclusions. The availability of CA125 results when patients attend for routine follow- up has improved their overall management in our clinics. It has reduced patient and physician anxiety and unsatisfactory out- of- clinic telephone communication. We recommend this change of practice to all Gynaecologic Oncology Centres engaged in active routine follow- up of their patients with epithelial ovarian cancer. Objectives. To evaluate the use of CA125 in the follow-up of women with epithelial ovarian cancer in the Cambridge Gynaecologic Oncology Centre. To institute changes depending on patients' preferences. Methods. A patient questionnaire was developed on follow-up, CA125 estimation and patient education in epithelial ovarian cancer and CA125. Initially, 100 patients were evaluated, and a change in practice was instituted. This was reevaluated using the same patient population. Results. 22/22 patients in clinic, and 68/78 patients who received the questionnaire by post, completed and returned it (n = 90) . 81% wanted CA125 results available at clinic fol- low-up visits, with 82% willing to have the blood test done at their GP surgery before attending outpatients. CA125 follow-up practice was changed accordingly. This change was re-evaluated. A second questionnaire was sent to 35 surviving patients from the first cohort.
机构地区 Department of Oncology
出处 《世界核心医学期刊文摘(妇产科学分册)》 2006年第6期55-56,共2页 Core Journal in Obstetrics/Gynecology
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