不同药物对根管治疗期间急症疗效的观察

The effects of different drugs on the incidence of acute inflammation in root canal treatment

目的:探讨替硝唑复合糊剂和甲醛甲酚液对慢性根尖周炎根管治疗期间急症的疗效差异。方法:选择慢性根尖周炎患者128例,168颗牙,随机分为两组,A组(替硝唑复合糊剂组)和B组(甲醛甲酚组),记录临床症状并拍摄X线片;常规进行根管预备后,A组用替硝唑地塞米松碘仿糊剂消毒根管,B组用甲醛甲酚纸尖消毒根管,1周后复诊、根充;记录临床症状,进行疗效评定,随访1.5a。结果:A组根管治疗期间急症的发生率明显低于B组(P<0.01),两组有显著性差异。1.5a后成功率比较,两组无显著性差异(P>0.05)。结论:替硝唑地塞米松碘仿糊剂作为根管消毒剂,对预防慢性根尖周炎根管治疗过程中急症的发生具有良好的作用,且远期效果可靠。

Objective： To observe the effects of tinidazole composite cataplasm and formaldehyde cresol solution on the incidence of acute inflammation in root canal treatment of chronic periodontitis patients. Methods： 128 chronic periodontitis patients were included, the 168 teeth were randomly divided into 2 groups. All patients underwent routine root canal preparation. In Group A （tinidazole composite cataplasm group）, the root canals were disinfected by tinidazole dexamethasone iodoform cataplasm, and in Group B （formaldehyde cresol solution group）, the root canals were disinfected by formaldehyde cresol paper tips. All patients then underwent root canal filling one week later, and they were followed up for 1.5 years. Their clinical symptoms were collected and the effects of the treatment were evaluated. Results： The incidence of acute inflammation in Group A was significantly higher than that of Group B （P〈0.01）. There was no significant difference in the success rate between 2 groups 1.5 years later （P〉0.05）. Conclusion： The tinidazole dexamethasone iodoform cataplasm is effective to prevent acute inflammation in the root canal treatment of chronic periodontitis, and it has reliable long term effects.