东莞地区儿童轮状病毒无症状感染的研究

Study on Asymptomatic Rotavirus Infection in Children in Dongguan

【目的】了解东莞地区儿童轮状病毒(RV)无症状感染的状况。【方法】收集东莞市人民医院2004年1月至2005年12月正常体检儿童粪便标本467例,采用酶联免疫吸附法(ELISA)检测RV。【结果】467例粪便标本检测到RV阳性标本115例,儿童RV无症状感染率为24.6%(115/467)。阳性标本主要来自6月龄至2岁儿童;检出高峰期在每年的10月至次年的2月。【结论】东莞地区儿童RV感染率较高,儿童RV无症状感染与RV有症状感染的特点呈一致性。

[Objective]To investigate the status of asymptomatic rotavirus（RV） infection of children in Dongguan. [Methods]Stool samples were collected from 467 healthy children without diarrhea in People＇s Hospital of Dongguan between January 2004 to December 2005. Enzyme linked immunosorbent assay was used to detect RV. [Results]Out of 467 samples investigated , 115 were RV positive. The overall prevalence of asymptomatic RV infection was 24.6% （115/467）. Most of the RV positive specimens were from children of 6 months to 2 years old. The peak positive rate for asymptomatic RV infection was from October to February of the following year. [Conclusion]RV infection rate is very high in children in Dongguan. The status of asymptomatic RV infection is similar to symptomatic RV infection.