脑内海绵状血管瘤的诊断与治疗

Cavernous Angioma of Brain

【目的】探讨脑内海绵状血管瘤的临床表现、影像学特点及治疗方法。【方法】回顾性分析本院1997年4月至2005年3月诊治的14例脑内海绵状血管瘤的临床诊治过程。【结果】14例病例中,10例经手术切除病变并经病理学证实,效果良好。2例行γ-刀治疗,病灶不缩小,临床症状未见明显改善。2例病人拒绝手术及γ-刀治疗,随访期间未见新的症状及病灶扩大。【结论】手术切除颞叶、额叶、顶叶脑内海绵状血管瘤较安全,既可切除病灶,还可根据情况切除致痫灶,使难治性癫痫获得缓解或消除癫痫发作,脑内海绵状血管瘤对放射治疗不敏感,对无症状或轻微症状者临床上可以不作处理。

[Objective]To discuss the clinical manifestation, radiological features and treatment of cavernous angioma of brain. [Methods]Fourteen cases of cavernous angioma of brain with clinical therapeutic process in our hospital between April 1997 and March 2005 were analysized. [Results]In fourteen cases, ten underwent surgery with excision of the lesions and got favorable results. Two patients were treated by gamma knife, the lesions didfft shrink, the clinical symptom was unchanged. Two patients didn＇t agree to treat, the lesions didn＇t enlarge in follow-up time. [Conclusion]Surgery can remove cavernous angioma of temporal lobe , frontal lobe and parietal lobe effectively and safely. For intractable epilepsy with cavernous angioma in temporal lobe lesions resection and temporal lobectomy should be done. Stererotactic radiation had no efficacy for cavernous angioma.