不孕症患者宫颈分泌物中CT、UU检测分析

Detection of Chlamydia trachomalis and Ureaplasma urealyticum in Cervical Secretions in Infertile Women

目的通过检测不孕症患者宫颈分泌物中沙眼衣原体(CT)、解脲支原体(UU)感染情况,探讨不孕与CT、UU感染的关系。方法采用聚合酶链反应(PCR)技术检测50例原发或继发不孕妇女(不孕组)及50例早孕妇女(对照组)宫颈分泌物中CT、UU感染情况。结果不孕组CT、UU感染率分别为28%、42%,显著高于对照组8%、12%(P<0.05)。结论CT、UU感染是导致不孕的重要因素。

Objective To study the association between infertility and infection with Chlamydia trachomalis （CT） and Ureaplasma urealyticum （UU）. Methods 50 infertile women （group Ⅰ） and 50 normal women （group Ⅱ） were examined in this study. Polymerase chain reaction（PCR） technique was used in the detection of CT- and UU-DNA prepared from cervical secretions. Results The percentage of samples from group Ⅰ showing CT- and UU-infectlon was 28% and 42%, respectively. The values were higher than the group Ⅱ control subjects （CT-infection;8%, UU-infection; 12%） （P〈0.05）. Conclusion CT- and UU-infection in cervix may be responsible for infertility.