摘要
目的:探讨近亲婚配现状及遗传效应,避免近亲婚配。方法:对近亲婚配引起反复流产、死胎或生育智力低下儿者,采用细胞遗传学技术,进行染色体检查,并对其进行核型分析。结果:检查夫妻之一核型异常的占5%,其后代核型异常占5%;夫妻双方核型正常,但反复流产、死胎或生后死亡的占90%。结论:不能排除近亲婚配是造成反复流产及后代异常的重要原因之一。
Objective: To analyze the actuality of consanguineous marriage and the offspring genetic effect. Methods: By the technique of cytogenetics , to analyze the chromosome of couples those who had the history of repeatedly abortion or childbearing history of dead foetus or mental retardation because of consanguineous mating. Results: The percentage of abnormal karyotype in one of a couple and in offspring were both 5%, and the percentage of couples both of whom had normal karyotype, but had the history of repeatedly abortion or dead foetus or postnatal death was 90%. Conclusion: It can not be eliminated that consanguineous marriage is an important reason that causing repeatedly abortion and abnormal offspring.
出处
《中国妇幼保健》
CAS
北大核心
2006年第14期1944-1945,共2页
Maternal and Child Health Care of China
关键词
近亲婚配
不良妊娠
遗传效应
Consanguineous marriage
Ⅲ - pregnancy
Genetic effect