摘要
目的观察并评价经眼动脉插管灌注尿激酶溶栓治疗视网膜中央动脉栓塞的疗效。方法经股动脉插管,应用微导管技术将导管插入眼动脉,局部灌注尿激酶25万～50万u进行溶栓治疗。结果8例中4例术后视力明显提高。6个月后视力达0.1～0.3者3例,高于0.3者1例。其中1例从光感提高到0.25,1例从术前0.1提高到0.6,1例从术前指数提高到0.3。3例术后视力提高不理想。1例从术前指数下降至光感。2例术后并发脑梗死伴肢体瘫痪。结论早期应用超选择眼动脉溶栓可能比其他治疗方法更有效,但应注意术中术后并发症。
Objective To investigate the effect of superselective ophthalmic artery thrombolysis for treatment of central retinal artery （CRAT）. Methods 250 000 - 500 000 u urokinase was directly perfused via ophthalmic artery （OA） through the retained superselective catheter after angiography into 8 eyes of 8 patients with CRAT. Results The visual acuity （VA） was significantly improved in 4 eyes. The VA of 3 eyes reached 0.1 - 0.3 after 6 months follow-up. The other 3 eyes achieved no significant improvement of VA. The VA of 1 eye decreased from finger count （FC） to light perception （LP）. Conclusions Early diagnosis and early superselective trans-micro catheter thrombolysis would be more effective than traditional treatment. （J Intervent Radiol, 2006, 15： 387-389）
出处
《介入放射学杂志》
CSCD
2006年第7期387-389,共3页
Journal of Interventional Radiology
关键词
视网膜中央动脉栓塞
溶栓治疗
尿激酶
Central retinal artery thrombosis
Thrombolytic therapy
Urokinase
