摘要
目的:比较甲基强的松龙(MP)与东莨菪碱(SCP)治疗急性脊髓损伤(ASCI)的治疗效果。方法:将44例ASCI患者随机分为3组,伤后8h以内患者随机分入大剂量MP治疗组及SCP治疗组,受伤时间超过8h的患者分入对照组。分别于入院时、伤后6周和6个月时对脊髓功能进行评分。结果:两治疗组的感觉功能在伤后6周和6个月时均有明显好转,运动功能MP治疗组在伤后6周时即有明显好转,而SCP治疗组在伤后6个月时才有明显好转。对照组患者脊髓功能恢复不明显。结论:MP与SCP均是治疗ASCI有效的药物,MP能够早期促进运动功能的恢复,对ASCI患者的康复有重要意义。
Objective：To compare effect of methylprednisolone and scopolamine in treating acute spinal cord injury.Method：44 cases were randomly divided into three groups.Cases managing in 8 hours post injury were divided into methylprednisolone group and scopolamine group.Cases managing beyond 8 hours post injury were divided into control group.Neurological functions were evaluated at admission,6 weeks and 6 months after injury.Result：Sensation status increased significantly at 6 weeks and 6 months in two experimental groups.Motion status increased at 6 weeks in methylprednisolone group and at 6 months in scopolamine group.Control group had no significant change of neurological function.Condusion：Methylprednisolone and scopolamine are effective in treating spinal cord injury.Methylprednisolone can promote early motion function recovery.
出处
《中国脊柱脊髓杂志》
CAS
CSCD
2006年第B07期17-19,共3页
Chinese Journal of Spine and Spinal Cord
关键词
脊髓损伤
甲基强的松龙
东莨菪碱
Spinal cord injury
Methylprednisolone
Scopolamine
