一阶导数分光光度法测定盐酸麻黄碱滴鼻剂的含量

First order derivative UV spectrophotometry of ephedrine hydrochloride nasal drops

本文采用一阶导数分光光度法，不经分离直接测定盐酸麻黄碱滴鼻剂的含量，可以消除尼泊金乙醋的干扰，在５～２５μｇ／ｍｌ的浓度范围内，具有良好的线性关系，ｒ＝０．９９９９（ｎ＝５）。平均回收率为９９．８３％，相对标准差为０．４９％。方法简便快速，结果准确。

The first order derivative UV spectrophotometry was for determination of ephedrine hydrochloride in its nasal drops to eliminate interference of ethyl p-hydroxyhenzoate.A good linearity has shown in the concentration of 5￣25μg/ml,r=0.9999(n=5).The average recovery was 99.83% and cv was 0.49%.The method is simple,rapid and accurate.