77例儿童恶性肿瘤停药后脏器功能随访报告

Function of viscera following cease of anticarcinogenic treatment in 77 childhood cases with malignant tumors

Objective To analysis the effect of chemotherapy on vital viscera in childhood malignant tumors. Methods Measurement of function of hematopoietic organ, liver, kidney and heart immunology and thyroid grand and detection of level of electric elements in serum and metabolism of calcium and phosphate in 77 childhood cases with malignant tumors. Results The average period of cease of anticarcinogenic treatment was 3 years(2 months to 10 years). Most of indicators of function were showed in normal limit for hematopoietic, liver, kidney, heart, immunology and thyroid grand as well as level of electric elements in serum in 77childhood cases with malignant tumors. All the results suggested that there were no obvious damage in function of vital viscera and no plain differences among various kinds of tumors. Conclusion The current scheme of anticarcinogenic treatment performed in our center showed safety and reliability without obvious damage in function of vital viscera as well. It is needed that further prolonged the following time, expended the samples and selected more sensitive laboratory indicators.