肝移植患者生活质量及相关因素的调查与分析

Analysis of the life quality and correlative factors of patients undergoing liver transplantation

目的探讨肝移植患者的生活质量及影响因素。方法用生活质量综合评定量表(GQOLI-74)对肝移植组和对照组各55例进行评估比较,对可能影响生活质量的因素进行单因素和多因素分析。结果①肝移植患者在躯体功能、社会功能方面低于正常人群,在物质功能、心理功能、生活质量总分方面与正常人群无显著性差异。②单因素分析显示,生活质量总分与面对、E量分、社会支持总分、主观社会支持呈正相关,与屈服、N量分、SAS、SDS呈负相关;躯体功能与E量分、主观社会支持呈正相关,与SAS、SDS呈负相关;社会功能与面对、E量分、社会支持总分、主观社会支持、移植时间、经济状况呈正相关,与屈服、N量分、SAS、SDS呈负相关。③多因素分析显示,对生活质量总分发生影响的因素依次为SDS、主观社会支持、重返工作岗位;对躯体功能发生影响的因素依次为SDS、疼痛;对社会功能发生影响的因素依次为SDS、疼痛、经济状况。结论肝移植患者的生活质量在躯体功能、社会功能维度较健康人群低,其生活质量受多种因素影响。

Objective Discuss the quality life and correlative factors of patients undergoing liver transplantation. Methods Applying general quality life inventory （GQOLI-74） to investigate the experimental group （n=55） and control group （n=55）. Experimental group were outpatients undergoing liver transplantation, and control group were healthy people. Correlate and regression analysis were used to study the correlated factors. Results ①The score on physical well-being and social well-belng in experimental group is lower than that of coutrol group. There were no significant difference in material well-being, psychological well being and health-related life quality total score. ②Correlate analysis show that the total score of GQOLI was positively correlated with confrontation, E score, social support and subject social support. It was negatively correlated with acceptance, N score, SAS and SDS. Physical well-being was positively correlated with E score and subject social support, while was negatively correlated with SAS and SOS. Social well-being was positively correlated with confrontation, E score, social support, subject social support, the time after liver transplantation and economic condition. It was negatively correlated with acceptance, N score, SAS and SOS. ③Regression analysis showed that the relative factors of quality of life were the total score of SOS, subject social support and return to work. The relative factors of physical well-being were SDS, pain. The relative factors of Social well-being were SOS, pain, economic condition. Conclusions The quality of life of patients undergoing liver transplantation was lower than healthy people, Many factors can correlate the patients quality of life.