电针四白穴对神经阻断大鼠胃肌电的影响

Influences of electroacupuncture at Sibai point on gastric myoelectricity in rats with nerve blockage

目的:探讨电针四白穴,对大鼠胃肌电兴奋途径．方法:大鼠32只,随机分为4组．选用ip抗胆碱能M受体阻断剂阿托品、交感神经节阻断剂六羟季胺和肾上腺素能神经阻断剂利血平,观察电针四白穴对神经阻断大鼠胃肌电的影响．结果:大鼠腹腔注射阿托品、六羟季胺后,慢波高活动相平均振幅、慢波高活动相时程／慢波周期比值以及快波平均峰簇数下降(P<0．01, P<0．05,P<0．01);注射利血平后,以上三种参数分别升高(P<0．01,P>0．05,P<0．01)．针刺四白穴能部分取消阿托品、六羟季胺对大鼠胃肌电的抑制效应(P<0．05或P>0．05)．结论:电针足阳明经四白穴对胃调控作用的外周通路既有胆碱能神经、交感神经系统的参与,又有肾上腺素能神经系统的参与．

AIM： To explore the mechanism of electroacupuncture （EA） at Sibai point in the excitement of gastric myoelectricity. METHODS： Thirty-two rats were randomly divided into group A, B, C and D. All the rats were electroacupunctured at Sibai Point. Meanwhile, the rats in group A, B, C and D were intraperitoneally injected with normal saline, atropine, hexamethonium and reserpine, respectively. The effects of EA at Sibai point on the gastric myoelectric activities in the rats were observed. RESULTS： After intraperitoneal injection of atropine and hexamethonium, the average am- plitude and ratio of period to time in the phase of high activity of gastric myoelectric slow wave, and the average numbers of the peaks of gastric myoelectric fast wave were significantly decreased （P 〈 0.01, P 〈 0.05, P 〈 0.01）, while after intraperitoneal injection of reserpine, the above three parameters were increased （P 〈 0.01, P 〉 0.05, P 〈 0.01）. EA at Sibai point partially relieved the inhibitory effect of atropine and hexamethonium on the gastric myoelectric activities in the rats （P 〈 0.05 or P 〉 0.05）. CONCLUSION： All the cholinergic, sympa- thetic and adrenergic nervous systems participate in the regulation and control of EA at Sibai point of Foot-Yangming meridian on gastrointestinal tract.