白血病病毒感染细胞系SRSV／3T3，A9的FN变化

The changes of fibronectin in SRSV/3T3 and A9 cell lines infected with leukemia Viruses

本文对本室建立的小鼠白血病病毒（ＭｕＬＶ）感染的ＳＲＳＶ一３Ｔ３细胞系与国际公认的Ｍｏｌｏｎｅｙ一ＭｕＬＶ感染的Ａ９细胞系间的Ｆｎ表达变化进行了比较研究。结果发现ＳＲＳＶ／３Ｔ３和Ａ９细胞表面的Ｆｎ荧光强度比正常成纤维细胞明显增强，并出现弥散分布的点状“强染点”，而在Ａ９和ＳＲＳＶ／３Ｔ３细胞的培养液中Ｆｎ含量却明显减少。

The change of expressed fibronectin SRSV/3T3 cell line which wasestablished by NIH/3T3 cells infected with SRS leukemia virus in our laboratory, was com-pared with A9 cell line infected with molo ney leukemia virus. The res ults showed that thefluo rescence intens ity on the cellular surfaees of SRSV/3T3 and A9 eells was stronger thanthat of normal fibroblasts of mouse, and the“strong stains”in dots were disseminated inthe SRSV/3T3 and A9 cells. However, the content of fibronectin in culture mediumof A9 and SRSV/3T3 cells was reduced significantly.The results mentioned abovewere discussed in this paper.