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脂质体疫苗抗原缓释系统 被引量:1

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摘要 脂质体(liposome)是人工合成的脂质双层微囊,具有可与细胞膜融合,可被吞噬细胞吞噬及能被充分生物降解的特点。设计良好的脂质体膜本身具有免疫佐剂活性。脂质体包裹抗原或编码抗原的DNA质粒,构成抗原缓释系统,可以经黏膜表面接种,有效诱导针对性的黏膜免疫;也能经皮肤、肌肉、静脉接种。脂质体缓释系统应能用于避孕疫苖接种技术的研究。
出处 《国外医学(计划生育.生殖健康分册)》 2006年第4期218-221,共4页
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同被引文献18

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  • 3郭秀侠,福泉,陈妍,徐军,夏滨,姜媛丽,胡晓明,于洪涛,盛军.人用狂犬病毒脂质体疫苗的制备及性质[J].中国生物制品学杂志,2006,19(6):589-591. 被引量:2
  • 4郝淑美,王亚军,戚凤春,李洪广.脂质体流感疫苗制备及体液免疫应答的研究[J].中国免疫学杂志,2007,23(3):263-266. 被引量:6
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