摘要
代谢物组学是近5年来发展起来的与基因组学、蛋白质组学等并列的学科。它运用核磁共振等分析技术,测定细胞和体液中内源性或外源性代谢物的经时变化,评价细胞功能和生物体的病理生理状态。本文综述其在新药开发中的作用。
Metabonomics is a new ＂ - omics＂ compared to genomics and proteomics, which developed in the last five years. NMR - based metabonomics describe the systemic response of organisms to physiological perturbations through time and get ＂ fingerfrint＂. The applying of metabonomics involves in many aspect. In this paper, the use of metabonomics in drug research is reviewed.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2006年第3期224-226,共3页
The Chinese Journal of Clinical Pharmacology
关键词
代谢物组学
核磁共振
代谢物
metabonomics
nuclear magnetic spectroscopy
metabolite
