重型颅脑外伤后早期急性肾功能衰竭的临床分析

Clinical analysis of early acute renal failure after the sever craniocerebral trauma

目的了解重型颅脑外伤患者早期发生急性肾功能衰竭的临床特点及防治。方法回顾性分析本院1998-01～2004—12重型颅脑外伤患者的临床资料，以重型颅脑外伤后24h是否出现急性肾功能衰竭为标准，将患者分为急性肾功能衰竭组和无急性肾功能衰竭组，对两组病例进行比较。结果182例重型颅脑外伤患者中，32例（17．6％）在颅脑损伤后24h发生急性肾功能衰竭，其中6例必须行肾脏替代治疗；重型颅脑外伤后早期发生急性肾功能衰竭者较无急性肾功能衰竭者死亡率高。结论重视重型颅脑外伤早期急性肾功能衰竭及其并发症，积极预防可改善病人预后。

Objective To investigate the clinical characteristics and treatments for prevention of the early acute renal failure in the patients with sever craniocerebral trauma. Methods A retrospective analysis was made on the clinical materials of the patients with sever craniocerebral trauma from January 1998 to December 2004 in our hospital. On the basis of whether the acute renal failure appeared after 24 hours＇ sever craniocerebral trauma,the patients were divided into acute renal failure group and the group without acute renal failure and the contrast was made on two groups. Results A total of 182 patients with sever craniocerebral trauma,32 cases （17. 6 %） had acute renal failure after 24 hours of brain in jury,among them 6 cases were given practice the kidney replacement therapy. The patients who suffered from acute renal failure after the sever craniocerebral trauma had a higher mortality than those who didn＇t suffer from acute renal failure. Conclusion： If the great importance is attached to the prevention for the acute renal failure and its complications after the sever craniocerebra trauma,the prognosis of patient can be improved.