婴幼儿金黄色葡萄球菌感染药敏分析

The analysis on susceptibility to staphylococcus aureus from respiratory tract of infants

目的:对从婴幼儿不同标本分离出的171株金黄色葡萄球菌进行鉴定和药敏分析,为婴幼儿科学治疗、合理保健及流行病学提供依据。方法:采用美国德灵公司生产的PC12阳性复合板、相关配套试剂及Microscanantoscn4自动细菌鉴定药敏分析仪分析。结果:171份标本中,痰液、咽拭子占58.5%;<1岁患儿占74.9%(128/171);万古霉素敏感率达95.9%、呋喃坦啶敏感率达94.7%、其他抗生素耐药率在15.2%～70.8%之间;MRSA占29.8%。结论:婴幼儿感染金黄色葡萄球菌应引起有关部门的关注。医院应加大MRSA的监测,合理使用抗生素,特别对婴幼儿更为重要。

Objective：TO analysis to drug-susceptivity of 171 straints staphylococcus aureus isolated from vairy sample of infants,in order to supply a scientific evidence for prevention and treatment of infection diseases occurring among infants, Methods： The PC12 positive drug sensitive test plate and its related reagents from Dade company,The drug susceptibivity were determined by Microscan antoscn-4 automatic analyzer,All of detecting results were judged according to the NCCLS standard, Results： ①82 strains of staphylococcus aureus were isolated from sputum of infants with infection, 18 strains were isolated from pharynx, the positive rate were 58.5 %. ②The infants inside thirty day after birth were found in 24 （41/171） ,less than one-year-old infants after birth were found in 50. 9% （51/171）, ③ Susceptibivity to vancomycin with 95.9% （164/171）, Susceptibility to Nitrofurantoin with 94, 7%（162/171） ,but resistance other drugs with 15.2-70. 8%. ④MRSA were examed up to 29.8%（51/ 171）. Conclusions： The infant infected by staphylococcus should be paid attention by woman child hospital and epidemoligists, MRSA should been detected, Reliable treated-drugs for infant were chosen to improve the clinical effect.