摘要
目的探讨Turcot综合征的内镜特点及遗传特性。方法回顾1976 ̄2004年所有结肠镜检查的患者,符合Turcot综合征定义的共有2例,结合文献,探讨该综合征的特点。结果家族性腺瘤样息肉病型1例为男性,55岁,遗传性非腺瘤病结直肠癌型(1ynch综合征)l例,为女性,58岁。两者均以结肠病变为首发症状,都死于脑部胶质细胞瘤。结论Turcot综合征为少见遗传病,对其加强监测,可早期诊断及时治疗,改善愈后。
[Objective] To discuss the endoscopic characteristics and hereditary of Turcot syndrome. [Method] We reviewed the patients who have been done colonoscopy from 1976 to 2004. Two cases of Turcot syndrome were found and the characteristic of the syndrome was discussed combined with literature. [Resultl One case suffered from familiar adenomatous polyposis, who is male and 55yrs old;The other is hereditary nonpolyposis colorectal cancer(Lynch syndrome),who is female and 58yrs old. Colonic change was showed first in both patients, and the cause to death for them is same: Glioblatoma in brain. [Conclusion] Tureot syndrome is a rare hereditary disease. If monitored carefully, it can be dignosed and treated in time.
出处
《中国内镜杂志》
CSCD
北大核心
2006年第7期764-764,767,共2页
China Journal of Endoscopy