α，α，2，6－四氯甲苯合成反应的色－质谱联用研究

SYNTHESIS OF α,α, 2,6 TETRACHLOROTOLUENE WITH GC/MS STUDY

本文利用ＧＣ、ＧＣ／ＭＳ研究了通过２－氯－６－硝基甲苯（Ａ）氯化制备α，α，２，６－四氯甲苯的反应过程。发现氯化首先在α－甲基上进行，生成α，２－二氯－６－硝基甲苯（Ｂ），Ｂ经硝基取代氯化（主要途径）生成α，２，６－三氯甲苯（Ｃ），Ｃ进一步发生α－氯代生成目的产物（Ｄ）。少量Ｂ还可经进一步的α－氯化形成α，α，２－三氯－６－硝基甲苯（Ｅ），Ｅ进一步发生硝基的氯取代而形成Ｄ。

The chlorination mechanism of 2 chloro 6 nitrotoluene(A) to α,α ,2,6 tetrachlorotoluene(D) has been studied by CM/MS.It is found that Cl attacks α H of A at first with the formation of an intermediate, α ,2 dichloro 6 nitro toluene (B) which turns subsequently to α ,2,6 trichlorotoluene(C) through denitrochlorination.C is then chlorinated on α H and forms D.Only a small amount of B is found to occure through another route to D,i.e.,via α,α ,2 trichloro 6 nitrotoluene(E) Ipso chlo rination to give 1,2,3 trichlorobnezene is also found to take place in the process.