老年与老年前期骨钙素和血钙的测定分析

Determination and Clinical Analysis of Serum Osteocalcin and Calcium in Middle and Old Age Healthy Subjects

对１５６例健康中老年人进行血清骨钙素和血清钙的含量测定，结果表明，血清骨钙素水平男性（３．４５±０．６７μｇ／Ｌ）要比女性（２．７９±０．７２μ／Ｌ）高，但两者都低于绝经后的妇女（４．０９±０．９８μｇ／Ｌ），而血钙随着增龄，有逐步下降的趋势．提示老年人，尤其是绝经后妇女由于骨转换加快，骨吸收增加会导致血清骨钙素含量升高，血钙下降．因此，临床上测定血清骨钙素和血钙浓度对衰老指标和骨代谢性疾病的研究有着重要的意义．

This paper presents the determination results of the serum osteocalcin and calcium in 156 middle and old age healthy. The results showed that the level of serum osteocalcin of the men (3. 45±0. 67μg/L) was higher than that of the women (2. 79±0. 72μg/L),but both were lower than that of postmenopausal women (4. 09±0. 98μg/L). Nevertheless, blood calcium has a descending tend with the increasing of age. These results suggest that the level of serum osteocalcin increased and blood calcim decreased in the aged and especially the postmenopausal women because of their accelerated bone turnover and increased bone absorption. Therefore,the determination of the serum osteocalcin for the study of the ageing and the bone metabolic diseases is important.