摘要
为了寻找高效、低毒的农药,设计合成了一系列新的含甲硫基和肟醚基的N-甲氧基氨基甲酸酯类化合物5a~5q,其结构经IR,1HNMR,LC/MS和元素分析确认.生物活性测定表明,部分化合物在50mg/L下对稻瘟病菌(Pyriculariaoryzae)、灰霉病菌(Botrytiscinerea)、水稻纹枯病菌(Rhizoctoniasolani)和小麦白粉病菌(Blumeriagriminis)有很好的抑菌活性.
In an attempt to find novel compounds with high activity and low toxicity, a series of novel N-methoxylcarbamates containing methylthio and oxime ethers 5a-5q were designed and synthesized according to bioisoster principle. Their structures were confirmed by ^1H NMR, IR, LC/MS spectra and elemental analysis. The prelimilary biological activity tests show that some compounds possess fungicidal activities against Pyricularia oryzae, Botrytis cinerea, Rhizoctonia solani and Blumeria griminis.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2006年第8期1115-1119,共5页
Chinese Journal of Organic Chemistry
基金
国家十五科技攻关(No.2004BA308A22)
湖南省杰出青年科学基金(No.04JJ1009)资助项目.