摘要
目的评价复方甘草酸苷治疗慢性乙型肝炎的疗效及不良反应。方法将87例患者随机分成两组,治疗组44例,给予复方甘草酸苷注射液100mL+5%葡萄糖注射液250mL/d,静脉滴注,1次/d,1个月后改为口服复方甘草酸苷片50mg,3次/d,连用两月为1个疗程;对照组43例,给予肝炎灵4mL/d,肌肉注射,3个月为1个疗程。两组均配合使用常规治疗药物,治疗2个疗程。结果疗程结束时,治疗组在临床症状及体征改善、肝功能复常方面均优于对照组,总有效率治疗组为90.9%,对照组为55.8%,差异显著(P<0.05),均未见严重的药物不良反应。结论复方甘草酸苷治疗慢性乙型肝炎疗效确切,值得临床推广。
Objective To explore the clinical efficacy and the side effects of stronger Neo-Minophagen C （SNMC） in treating chronic hepatitis B. Methods 87 patients were rardomly divided into two groups. 44 patients as the treatment group received SNMC injection 100 mL ＋5% glucose 250 mL injection, i.v. drip, q. d. for one month. Then the dose of SNMC changed to 50 mg p. o.,t. i. d. for two months as a treatment period. 43 patients as the control group were given caryophyllin 4 mL i. m., q. d. for two month. Results After completion of therapy, the clinical syndromes and the liver function of the treatment group were much better than those of the control group. The general effective rate was 90.9% in the treatment group and 55.8% in the control group （P〈O. O5）.Side effects were not found. Conclusion SNMC is effective agent in the treatment of chronic hepatitis B.
出处
《中国药业》
CAS
2006年第12期49-50,共2页
China Pharmaceuticals
