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雄激素替代治疗Klinefelter综合征 被引量:5

Replacement therapy of androgen in the managementof klinefelter's syndrome
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摘要 本文报道经临床及染色体分析证实的47例Klinefelter综合征患者,其中36例连续使用睾酮治疗1年以上,青春发育顺序以阴毛生长最快,其次为腋毛和胡须,最后为喉节。阴茎长度从5.26cm增长到8.23cm,睾丸容积右侧从3.1ml增大到4.8ml,左侧从3.09ml到4.70ml,精液量从0.5~1ml增多到1.5~4.4ml,说明睾丸酮有促发附属性腺分泌功能。但患者仍不育。睾丸酮治疗3月后患者性功能即有明显改善。 Clinical feature and sexual hormone of 47 cases with Klienefelter's Syndrome proved by analysis of karyotype were analyzed in our laboratory. These results show that these patient were characterized by small testes, azoospermia, increasing in serum FSH, LH and decreasing in serum testosterone. 36 cases received replacement therapy of androgen. After one year therapy, pubes growth is the fastest, and the next is axillary hair, beard and laryngeal protuberance. The length of penis is increased from 5.26cm to 8.23cm. Volume of right testis is increased from 3.1ml to 4.81ml, and left testis is from 3.09ml to 4.70ml. Volume of semen is increased from 0.5~1ml to 1.5~4.4ml. The conclusion is that androgen has the function to enhance the function of accessory sexual gland. The patients remained infertle. Sexual function of patients got better after the therapy by androgen.
出处 《男性学杂志》 CSCD 1996年第3期160-162,共3页
关键词 睾丸酮 克氏综合征 治疗 Androgen Klinefelter Syndrome Therapy
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