摘要
Infectious bursal disease virus (IBDV) was inactivated by two different chemicals—formaldehyde and binary ethylenimine (BEI). Formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.
Infectious bursal disease virus （IBDV） was inactivated by two different chemicals-formaldehyde and binary ethylenimine （BEI）. Formaldehyde was used at 0. 1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.
基金
Project (No. PSF/Res/P-AU/Bio (246)) supported by Pakistan Sci-ence Foundation (PSF)
关键词
IBDV
二元乙烯亚胺
甲醛
免疫响应
传染病
小鸡
Infectious bursal disease virus （IBDV）, Binary ethylenimine （BEI）, Formaldehyde, Immune response
