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胆固醇酯转运蛋白抑制剂研究进展 被引量：5

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摘要 升高高密度脂蛋白胆固醇水平是降低动脉粥样硬化危险的一个可能的有益治疗靶标。胆固醇酯转运蛋白抑制剂虽然能有效升高高密度脂蛋白胆固醇水平,但目前对其是否能有效减少动脉粥样硬化的危险程度尚不明确。
作者 董劭壮 赵水平
机构地区 中南大学湘雅二医院心内科
出处 《中国动脉硬化杂志》 CAS CSCD 2006年第6期550-552,共3页 Chinese Journal of Arteriosclerosis
关键词 内科学 胆固醇酯转运蛋白抑制剂研究进展 综述 胆固醇酯转运蛋白抑制剂 高密度脂蛋白胆固醇 动脉粥样硬化
分类号 R5 [医药卫生—内科学]
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参考文献20

  • 1Li X,Chyu KY,Faria Neto JR,Yano J,Nathwani N,Ferreira C,et al.Differential effects of apolipoprotein AⅠ-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice[J].Circulation,2004,110:1 701-705
  • 2Nissen SE,Tsunoda T,Tuzcu EM,Schoenhagen P,Cooper CJ,Yasin M,et al.Effect of recombinant apoAⅠ Milano on coronary atherosclerosis in patients with acute coronary syndromes:a randomized controlled trial[J].JAMA,2003,290 (17):2 292-300
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  • 6郑克勤,张克兰,张思仲.胆固醇酯转运蛋白与动脉粥样硬化[J].中国动脉硬化杂志,2002,10(5):454-457. 被引量：2
  • 7Barter PJ,Brewer HB Jr,Chapman MJ,Hennekens CH,Rader DJ,Tall AR.Cholesteryl ester transfer protein:a novel target for raising HDL and inhibiting atherosclerosis[J].Arterioscler Thomb Vasc Biol,2003,23:160-167
  • 8Boekholdt SM,Kuivenhoven JA,Wareham NJ,Peters RJ,Jukema JW,Luben R,et al.Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women:the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study[J].Circulation,2004,11:1 418-423
  • 9Rittershaus CW,Miller DP,Thomas LJ,Picard MD,Honan CM,Emmett CD,et al.Vaccine-induced antibodies inhibit CETP activity in vivo and reduce aortic lesions in a rabbit model of atherosclerosis[J].Arterioscler Thromb Vasc Biol,2000,20:2 106-112
  • 10Davidson MH,Maki K,Umporowicz D,Wheeler A,Rittershaus C,Ryan U.The safety and immunogenicity of a CETP vaccine in healthy adults[J].Atherosclerosis,2003,169:113-120

二级参考文献30

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中国动脉硬化杂志
2006年 第6期

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