布洛芬和对乙酰氨基酚治疗小儿感染性发热疗效比较

Comparison of curative effect of ibuprofen and paracetamol on infantile infection fever

目的：了解布洛芬混悬液（美林）治疗儿童感染性发热的有效性和安全性，为临床选择1：1服退热药提供参考。方法：116例急性上呼吸道感染伴发热的患儿随机分为两组。治疗组72例，对照组44例，分别给予布洛芬（美林）和对乙酰氨基酚（泰诺林）治疗。结果：两组在服药后2h内退热的有效率分别为98．6％、95．5％，差异无统计学意义（P〉0．05），但对照纽从服药自3～4h开始体温呈现回升趋势，而治疗组在服药后能雏持7～8h体温不回升，显效率分别为95．8％、70．5％，差异有统计学意义（P〈0．01）。结论：布洛芬混悬液退热作用强，维持时间久。

Objective： To observe the validity and security of ibuprofen suspension in treating enfant fever heat of infection, thence provide reference to help choose oral febrifuge in clinic. Methods： 116 patients of urgent breathing infection going with fever were divided into two groups, the treatment group of 72 cases and the control group of 44 cases, administered with ibuprofen and paracetamol respectively. Results： After the two groups took medicine, the difference in deferveseeing was not significant within 2 hours, and the efficiency ratios were 98.6% and 95.5%, without statistics significance （P 〉 0.05）. But after 3 -4 hours, the fever in the control group began to rise again, but the treatment group kept quite satisfying efficiency in deferveseeing 7 - 8 hours after taking medicine, with their obvious efficiencies as 95.8 % and 70.5 %, a difference with statistics significance （P 〈 0.01 ）. Conclusions： Ibuprofen shows a great and long function of deferveseeing.