椎管原发性非何杰金氏恶性淋巴瘤临床与病理分析（附七例报告）

Clinical and Pathological Study of Primary Non-Hodgkin's Lymphoma from Verterbra (A Report of 7 Cases)

用免疫学及组织化学方法对７例原发于脊椎骨的非何杰金氏恶性淋巴瘤（ＮＨＬ）进行了回顾性研究。免疫学分型发现了Ｂ细胞型４例、Ｔ细胞型１例、混合型２例。组织学分型低度恶性２例、中度恶性３例、高度恶性２例。其中淋巴浆细胞样型预后最好。术前无一例考虑到本病。鉴别诊断时应除外骨髓瘤、尤文氏瘤、转移性未分化癌和小细胞性骨肉瘤。病变晚期区别是脊椎骨原发还是脊髓原发的ＮＨＬ较为困难。如能肯定为弥漫型或瘤细胞仅限于白质则对前者的确立有帮助。

Seven cases of Non-Hodgkin's lymphoma (NHL) from verterbra were studied retrospectively by histological and immunohistochemical methods in clinic and pathology. The resultsshowed 4 cases of B cell type, 1 case of T cell type and 2 cases of mixed type,immunologically. Also 2 cases of low malignency, 3 cases of moderate malignency and 2 cases of high malignency,histologically. The prognosis of lymphoplasmoid type is the best. NHL wasn' t taken into account in all patients by physicians,though their signs had showed obvious space occupying features. Myeloma, Ewing's tumor, metastatic undifferential cancer and ostecsarcoma (small cell type) should be ruled out in differential diagnosis. It is rather difficult to decide whether the tumor is primarily from verterbra or spinal cord,especially in late stage. If atumor is confirmed as difuse type and limmited only in white matter,it is probably helpful indetermining its primary position.