北京城乡老年人高血压与抑郁的关系

Hypertension and related depression among elderly residents in the community of Beijing

目的分析北京市城乡老年人血压与应用抑郁量表(CES-D)检测出的抑郁症状的关系。方法于2000年对一个流行病学队列研究人群2 656例老年人进行血压测量及CES-D的检查,同时进行人口学因素及慢性病情况的调查。结果2 656例老人平均收缩压为(141.16±23.88)mm Hg(1 mm Hg=0.133 kPa),平均舒张压为(80.28±12.15)mm Hg。CES-D平均得分(6.89±9.05)分。其中有抑郁症状者362例(13.6%)。收缩压≥160 mm Hg者抑郁发生率为16.9%,舒张压≥90 mm Hg者抑郁发生率为18.4%,分别显著高于收缩压<160 mm Hg者(12.8%)和舒张压<90 mm Hg者(12.2%),分层分析显示,女性、年龄<75岁、不吸烟的老人收缩压及舒张压增高者抑郁症状出现的比例增大;居住于城市、非文盲、已知有高血压史、高血压史10年以上的老人收缩压增高更易出现抑郁症状;而居住于农村、文盲、高血压史小于10年的老人舒张压增高更易出现抑郁症状。多元logistic回归分析显示,舒张压增高、慢性病史、女性、文盲、农村老人易患抑郁。结论老年人血压增高与抑郁相关。

Objective To investigate the association between blood pressure and depression detected with CES-D in the elderly community residents in Beijing. Methods 2 656 Beijing elderly residents in a cohort study in year 2000 were examined and screened with CES-D and blood pressure. Demographic data, information of health status were also collected. Results The mean systolic blood pressure, diastolic blood pressure and CES-D score were 141.16± 23.88 mm Hg, 80.28± 12.15 mm Hg and 6.89 ± 9.05 respectively. The rate of depression in this cohort was 13.6%（362/2656）. The proportion of depression in the aged with SBP≥160 mm Hg or DBP≥90 mm Hg was significantly higher than that in those with SBP〈 160 mm Hg or DBP〈 90 mm Hg respectively. Further stratified observation showed that female, age less than 75 and non-smoking elderly residents who had high SBP and DBP had large proportion of depression. The urban literate residents with high SBP and high blood pressure history for more than 10 years had significantly high rate of depression. The rural illiterate residents with high DBP and high blood pressure history for less than 10 years also had significantly high rate of depression. Logistic regression analysis indicated that increased diastolic blood pressure, poor health status, female, illiterate and rural aged were correlated to depression. Conclusion High blood pressure is correlated with depression in elderly residents.